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This 5-ingredient Mississippi chicken recipe is really easy to make and perfectly juicy! The signature pepperoncini ranch sauce tastes zesty and amazing.

I think you’ll also enjoy my Creamy Lemon and Herb Pot Roasted Chicken.

a slow cooker with Mississippi chicken

Why you’ll love it

You’ve probably heard of Mississippi Pot Roast already since it’s so popular, and I’m happy to bring you similar flavors with chicken! It’s super simple to throw together and has an irresistibly tasty savory sauce with pepperoncini peppers.

The magical buttery sauce keeps the chicken nice and moist as it cooks, and then it’s fall-apart tender. Absolute perfection. I love the little kick from the peppers. This Crockpot Mississippi chicken is a family-friendly pantry recipe that will go on repeat and makes fantastic leftovers!

What you’ll need

  • Chicken – we’re using boneless skinless chicken breasts
  • Pepperoncini peppers – these peppers and brine give the sauce its tangy quality. Find them in a jar in the pickle aisle.
  • Au jus mix – get one labeled au jus gravy. It’s different than regular gravy.
  • Ranch seasoning – I prefer Hidden Valley, but use your favorite
  • Butter – for adding luxurious, buttery goodness. Make sure to use unsalted since the seasoning and au jus already contain salt.
ingredients for mississippi chicken on a counter

Helpful tips

  • This recipe has a bit of a kick, but as written, it’s not too spicy. Out of all the hot peppers out there, pepperoncini peppers are fairly mild. If you want it to have more kick, you can go ahead and the whole jar of peppers!
  • The chicken should shred easily with two forks. If it doesn’t, simply give it a little more time. I usually cook mine on high for 3.5 hours.

How to make Mississippi chicken

This is an overview with step-by-step photos. Full ingredients & instructions are in the recipe card below.

a slow cooker with Mississippi chicken before and after cooking

Add the chicken to your slow cooker, followed by pouring in the pepperoncini juice. Add in the contents of the packets, and arrange the remaining ingredients around and on top of the chicken. Once cooked, shred with two forks and enjoy.

Tools for this recipe

Check out Natasha’s favorite kitchen essentials, gadgets, and cookware!

Substitutions and variations

  • If salt is a concern, you can use a Homemade Ranch Seasoning vs. the packaged kind.
  • You may want to use chicken thighs instead of chicken breasts, especially if you’re planning on cooking it for 8 hours on low heat. Chicken breasts are very lean and can dry out quite easily. I’d use 6-8 boneless skinless chicken breasts depending on their size (you want about 2 lbs. or so).
  • If you prefer to make oven baked Mississippi chicken, use a 9×13 baking dish and cook at 375F, uncovered, for about 40 minutes, or until the chicken is 165F in the middle.

What to serve with Mississippi chicken

  • It’s great over mashed potatoes. Try my classic Garlic Mashed Potatoes, or change it up with these Boursin Mashed Potatoes. Rice works well too!
  • It’s also delicious served in a bun with some coleslaw or sweet pickles and mayo for Mississippi chicken sandwiches, or you could serve them as tacos.

Leftovers and storage

  • Store leftover slow cooker Mississippi chicken for 3-4 days in the fridge.
  • Reheat over a low heat until warmed through.
  • You can freeze this one for up to 3 months, but be aware chicken breasts can dry out more in the freezer.
a bowl with Mississippi chicken over mashed potatoes

If you made this Mississippi chicken recipe, I’d love it if you left a star rating and review in the comments below! You can also find me on Instagram.

a slow cooker with Mississippi chicken
5 from 6 votes

Mississippi Chicken

This 5-ingredient Mississippi chicken recipe is really easy to make and perfectly juicy! The signature pepperoncini ranch sauce tastes zesty and amazing.
Prep: 5 minutes
Cook: 3 hours
Total: 3 hours 5 minutes
Servings: 6

Equipment

Ingredients 

  • 4 large chicken breasts boneless skinless
  • 12 pepperoncini peppers + 1/4 cup juice from the jar
  • 1 (1 ounce) packet ranch seasoning mix I use Hidden Valley
  • 1 (1 ounce) packet au jus seasoning
  • 1/2 cup unsalted butter (1 stick) cut into pieces

Instructions 

  • Add the chicken breasts to your slow cooker. Pour in the pepperoncini juice and then add the peppers on/around the chicken. Sprinkle the chicken with the ranch and au jus seasoning, and then place the butter on top. Cover and cook for 3-4 hours on high or 6-8 hours on low.
  • Shred the chicken with two forks, toss with the sauce, then serve and enjoy.

Notes

  • Chicken breasts can dry out, so if you’re planning on cooking it for the full 8 hours, you may want to swap with boneless skinless chicken thighs as they hold up better to slow cooking.
  • This recipe is quite salty, so be sure to use unsalted butter and taste before adding any extra salt.
  • Adapted from my Mississippi Pot Roast recipe.
  • Nutritional information is provided as a courtesy only and should be construed as an estimate rather than a guarantee. Ingredients can vary and Salt & Lavender makes no guarantees to the accuracy of this information.
     

Nutrition

Calories: 326kcal, Carbohydrates: 4g, Protein: 33g, Fat: 19g, Saturated Fat: 11g, Polyunsaturated Fat: 1g, Monounsaturated Fat: 5g, Trans Fat: 1g, Cholesterol: 137mg, Sodium: 552mg, Potassium: 613mg, Fiber: 1g, Sugar: 0.4g, Vitamin A: 586IU, Vitamin C: 18mg, Calcium: 15mg, Iron: 1mg

Nutrition information is automatically calculated, so should only be used as an approximation.

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Hi! Iā€™m Natasha.

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22 Comments

  1. Hello šŸ˜€ Can you clarify what the rough total weight of the chicken should be before cooking? I’m a little confused about that part. I have 4 huge breasts that weigh between 4.5 and 5lbs total. How much of that should I use?

    Thank you!

    1. Hi! I’d do up to about 2.5 pounds in one go unless you double the recipe, and then cook time will likely need to increase as they will be stacked (and I have not tested doing this). I fit the pictured 4 chicken breasts (see ingredients photo) into the slow cooker side-by-side, and they were a bit over 2 lbs. total. Hope this helps!